Amantadine for COVID-19 treatment (ACT study): a randomized, double-blinded, placebo-controlled clinical trial
Description
CONCLUSIONS: We found no effect of amantadine on disease progression of SARS-CoV-2 infection.
PubMed COVID-19 Clinical Care
38241 - 38250 of 58470 results found
How do Orphan Disease Patients Live Under the Pandemic of Omicron Variant? - A Nationwide Survey of Spinal Muscular Atrophy Patients in China
Description
CONCLUSIONS: This is the first large-sample survey to timely reveal the living situation of SMA patients under the pandemic of Omicron variant. Patients with SMA type 1 should be paid more attention in terms of hospitalization and ICU stay.
Transmission and re-infection of Omicron variant XBB.1.5 in hamsters
Description
BACKGROUND: Like its predecessors in the XBB family, XBB.1.5 is highly immune evasive from therapeutic monoclonal antibodies and neutralizing antibodies generated by vaccination and/or infection. However, there is a lack of in vivo data on XBB.1.5 in
Cognition and psychological well-being in adults with post COVID-19 condition and analyses of symptom sequelae
Description
CONCLUSIONS: This study contributes to the literature regarding post COVID-19 condition in adults including the relationship between the cognitive and psychological symptoms. Results are summarized in key clinical learning points.
COVID-19 Infection Is Associated With Increased In-Hospital Mortality and Complications in Patients With Acute Heart Failure: Insight From National Inpatient Sample (2020)
Description
Introduction: Patients with acute heart failure (AHF) exacerbation are susceptible to complications in the setting of COVID-19 infection. Data regarding the clinical outcomes of COVID-19 in patients admitted with AHF is limited. Methods: We used the
In silico-based screening of natural products as potential inhibitors of SARS-CoV-2 macrodomain 1
Description
The rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) worldwide has led to over 600 million cases of coronavirus disease 2019 (COVID-19). Identifying effective molecules that can counteract the virus is imperative. SARS-CoV
Detecting Clinically Relevant Emotional Distress and Functional Impairment in Children and Adolescents: Protocol for an Automated Speech Analysis Algorithm Development Study
Description
CONCLUSIONS: This study contributes to the literature as it addresses the need for speech-focused digital health tools to detect clinically relevant emotional distress and functional impairments in children and adolescents. The preliminary results
Electrochemical biosensor strategy combining DNA entropy-driven technology to activate CRISPR-Cas13a activity and triple-stranded nucleic acids to detect SARS-CoV-2 RdRp gene
Description
By merging DNA entropy-driven technology with triple-stranded nucleic acids in an electrochemical biosensor to detect the SARS-CoV-2 RdRp gene, we tackled the challenges of false negatives and the high cost of SARS-CoV-2 detection. The approach
Prevalence of Digital Eye Strain Among University Students and Its Association with Virtual Learning During the COVID-19 Pandemic
Description
CONCLUSION: In the wake of the COVID-19 pandemic, virtual learning has become an integral part of education, leading to increased use of digital technology. The aim of this study was to investigate the impact of virtual learning on eye strain and to
COVID-19 Vaccine Evolution and Beyond
Description
In December 2019, a new severe acute respiratory syndrome coronavirus-2 (SARS CoV-2) was first reported in China. It would quickly spread and emerge as a COVID-19 pandemic. The illness caused by SARS CoV-2 would fall on a clinical spectrum ranging