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PubMed COVID-19 Clinical Care

35931 - 35940 of 58470 results found

DAPTEV: Deep aptamer evolutionary modelling for COVID-19 drug design

Date
Wednesday, July 05, 2023 - 4:00 AM
Description
Typical drug discovery and development processes are costly, time consuming and often biased by expert opinion. Aptamers are short, single-stranded oligonucleotides (RNA/DNA) that bind to target proteins and other types of biomolecules. Compared with

First sequenced cases of Omicron BA.2 sublineage in Ecuador

Date
Wednesday, July 05, 2023 - 4:00 AM
Description
The largest wave of infection with SARS-CoV-2 virus in Ecuador was observed in mid-December 2021 and early January 2022, driven by B.1.1.529/BA (Omicron) variant. During the second half of March, an increase in the number of daily cases was observed

Safety and Immunogenicity against Ancestral, Delta and Omicron Virus Variants Following a Booster Dose of an Inactivated Whole-Virus COVID-19 Vaccine (VLA2001): Interim analysis of an open-label extension of the randomized, controlled, phase 3 COV-COMP...

Date
Wednesday, July 05, 2023 - 4:00 AM
Description
CONCLUSION: A booster dose of VLA2001 was safe and well tolerated after primary immunization with VLA2001 and ChAdOx1-S. The tolerability of a booster dose of VLA2001 was similar to the favourable profile observed after the first and second priming